Cargando…
Design and Synthesis of Fluoro Analogues of Vitamin D
The discovery of a large variety of functions of vitamin D(3) and its metabolites has led to the design and synthesis of a vast amount of vitamin D(3) analogues in order to increase the potency and reduce toxicity. The introduction of highly electronegative fluorine atom(s) into vitamin D(3) skeleto...
Autores principales: | Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348876/ https://www.ncbi.nlm.nih.gov/pubmed/34360956 http://dx.doi.org/10.3390/ijms22158191 |
Ejemplares similares
-
The Synthesis and Biological Evaluation of D-Ring-Modified Vitamin D Analogues
por: Kawagoe, Fumihiro, et al.
Publicado: (2021) -
Stereoselective Synthesis of 24-Fluoro-25-Hydroxyvitamin D(3) Analogues and Their Stability to hCYP24A1-Dependent Catabolism
por: Kawagoe, Fumihiro, et al.
Publicado: (2021) -
Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated
Vitamin D(3) Analogues
por: Kawagoe, Fumihiro, et al.
Publicado: (2019) -
The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D(3) and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities
por: Mototani, Sayuri, et al.
Publicado: (2022) -
Novel Vitamin D Analogs for Prostate Cancer Therapy
por: Chen, Tai C., et al.
Publicado: (2011)