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Bidentatide, a Novel Plant Peptide Derived from Achyranthes bidentata Blume: Isolation, Characterization, and Neuroprotection through Inhibition of NR2B-Containing NMDA Receptors

Increasing attention is being focused on the use of polypeptide-based N-methyl-d-aspartate (NMDA) receptor antagonists for the treatment of nervous system disorders. In our study on Achyranthes bidentata Blume, we identified an NMDA receptor subtype 2B (NR2B) antagonist that exerts distinct neuropro...

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Detalles Bibliográficos
Autores principales: Ding, Fei, Bai, Yunpeng, Cheng, Qiong, Yu, Shu, Cheng, Mengchun, Wu, Yulin, Zhang, Xiaozhe, Liang, Xinmiao, Gu, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348887/
https://www.ncbi.nlm.nih.gov/pubmed/34360755
http://dx.doi.org/10.3390/ijms22157977