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Two Crystal Forms of a Hydrated 2:1 β-Cyclodextrin Fluconazole Complex: Single Crystal X-ray Structures, Dehydration Profiles, and Conditions for Their Individual Isolation

Inclusion complexes between cyclodextrins (CDs) and active pharmaceutical ingredients (APIs) have potential for pharmaceutical formulation. Since crystallization of a given complex may result in the isolation of multiple crystal forms, it is essential to characterize these forms with respect to thei...

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Detalles Bibliográficos
Autores principales: Sala, Andrea, Hoossen, Zakiena, Bacchi, Alessia, Caira, Mino R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348925/
https://www.ncbi.nlm.nih.gov/pubmed/34361579
http://dx.doi.org/10.3390/molecules26154427