Cargando…

Protein Arginine Methyltransferase (PRMT) Inhibitors—AMI-1 and SAH Are Effective in Attenuating Rhabdomyosarcoma Growth and Proliferation in Cell Cultures

Rhabdomyosarcoma (RMS) is a malignant soft tissue cancer that develops mostly in children and young adults. With regard to histopathology, four rhabdomyosarcoma types are distinguishable: embryonal, alveolar, pleomorphic and spindle/sclerosing. Currently, increased amounts of evidence indicate that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janisiak, Joanna, Kopytko, Patrycja, Tkacz, Marta, Rogińska, Dorota, Perużyńska, Magdalena, Machaliński, Bogusław, Pawlik, Andrzej, Tarnowski, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348967/ https://www.ncbi.nlm.nih.gov/pubmed/34360791 http://dx.doi.org/10.3390/ijms22158023

Ejemplares similares

Garcinol and Anacardic Acid, Natural Inhibitors of Histone Acetyltransferases, Inhibit Rhabdomyosarcoma Growth and Proliferation
por: Tomasiak, Patrycja, et al.
Publicado: (2023)

Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivo
por: Tarnowski, Maciej, et al.
Publicado: (2017)

Garcinol—A Natural Histone Acetyltransferase Inhibitor and New Anti-Cancer Epigenetic Drug
por: Kopytko, Patrycja, et al.
Publicado: (2021)

Adiponectin Is a Component of the Inflammatory Cascade in Rheumatoid Arthritis
por: Łączna, Małgorzata, et al.
Publicado: (2022)

Differential effect of adenosine on rhabdomyosarcoma migration and proliferation
por: Tarnowski, Maciej, et al.
Publicado: (2018)

Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis
por: Piotrowska, Katarzyna, et al.
Publicado: (2020)

Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
por: Feoli, Alessandra, et al.
Publicado: (2023)

Structure and Function of Protein Arginine Methyltransferase PRMT7
por: Halabelian, Levon, et al.
Publicado: (2021)

Protein arginine methyltransferase 5 (PRMT5) dysregulation in cancer
por: Shailesh, Harshita, et al.
Publicado: (2018)

Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons
por: Dong, Rui, et al.
Publicado: (2021)

Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase
por: Cura, Vincent, et al.
Publicado: (2021)

The arginine methyltransferase PRMT5 promotes mucosal defense in the intestine
por: Hernandez, Juan E, et al.
Publicado: (2023)

The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation
por: Bai, Xuemei, et al.
Publicado: (2022)

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification
por: Ito, Tatsuo, et al.
Publicado: (2009)

KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5
por: di Caprio, Roberta, et al.
Publicado: (2015)

Characterization of protein arginine methyltransferase of TgPRMT5 in Toxoplasma gondii
por: Liu, Min, et al.
Publicado: (2019)

PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development
por: Wang, Bingyuan, et al.
Publicado: (2021)

Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells
por: Rasheed, Shayaan, et al.
Publicado: (2023)

Protein arginine methyltransferases PRMT1, PRMT4/CARM1 and PRMT5 have distinct functions in control of osteoblast differentiation
por: Dashti, Parisa, et al.
Publicado: (2023)

Arginine methyltransferases PRMT2 and PRMT3 are essential for biosynthesis of plant-polysaccharide-degrading enzymes in Penicillium oxalicum
por: Zhao, Shuai, et al.
Publicado: (2023)

ADCY5, CAPN10 and JAZF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes
por: Ustianowski, Przemysław, et al.
Publicado: (2021)

Epigenetic Regulation of Inflammatory Responses in the Context of Physical Activity
por: Tarnowski, Maciej, et al.
Publicado: (2021)

The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility
por: Azhar, Muhammad, et al.
Publicado: (2023)

The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation
por: Kleinschmidt, Markus A., et al.
Publicado: (2008)

The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors
por: Sun, Yutong, et al.
Publicado: (2019)

The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer
por: Choucair, Ali, et al.
Publicado: (2019)

Arginine Methyltransferase PRMT1 Regulates p53 Activity in Breast Cancer
por: Liu, Li-Ming, et al.
Publicado: (2021)

The expression of myogenic microRNAs indirectly requires protein arginine methyltransferase (Prmt)5 but directly requires Prmt4
por: Mallappa, Chandrashekara, et al.
Publicado: (2011)

Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4)
por: Gunnell, Emma A., et al.
Publicado: (2020)

Expression of markers of neural stem and progenitor cells in glioblastoma multiforme in relation to tumor recurrence and overall survival
por: Wańkowicz, Paweł, et al.
Publicado: (2020)

Effect of Bortezomib on Global Gene Expression in PC12-Derived Nerve Cells
por: Łuczkowska, Karolina, et al.
Publicado: (2020)

Genome wide comparative analysis of the effects of PRMT5 and PRMT4/CARM1 arginine methyltransferases on the Arabidopsis thaliana transcriptome
por: Hernando, Carlos E, et al.
Publicado: (2015)

Identification and Characterization of New Molecular Partners for the Protein Arginine Methyltransferase 6 (PRMT6)
por: Lo Sardo, Alessandra, et al.
Publicado: (2013)

Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8
por: Runqe, Sarah, et al.
Publicado: (2013)

The Arginine Methyltransferase PRMT6 Cooperates with Polycomb Proteins in Regulating HOXA Gene Expression
por: Stein, Claudia, et al.
Publicado: (2016)

Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)
por: Kaniskan, H. Ümit, et al.
Publicado: (2017)

Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors
por: Lin, Hong, et al.
Publicado: (2019)

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD
por: Günes Günsel, Gizem, et al.
Publicado: (2022)

Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis
por: Lai, Yandong, et al.
Publicado: (2023)

The Critical Role of Protein Arginine Methyltransferase prmt8 in Zebrafish Embryonic and Neural Development Is Non-Redundant with Its Paralogue prmt1
por: Lin, Yu-ling, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_bgdp588osrvnvg9gcn1280l88u