AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout

The Bruch’s membrane (BrM) is a five-layered extracellular matrix (ECM) that supports the retinal pigment epithelium (RPE). Normal age-related changes in the BrM may lead to RPE cell damage and ultimately to the onset and progression of age-related macular degeneration (AMD), which is the most commo...

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Detalles Bibliográficos
Autores principales: Chinchilla, Blanca, Fernandez-Godino, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348968/
https://www.ncbi.nlm.nih.gov/pubmed/34360950
http://dx.doi.org/10.3390/ijms22158183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348968/
https://www.ncbi.nlm.nih.gov/pubmed/34360950
http://dx.doi.org/10.3390/ijms22158183

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