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Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis

INTRODUCTION: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have...

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Autores principales: Bartimote, Christopher, Fraser-Bell, Samantha, Dunn, Hamish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349080/
https://www.ncbi.nlm.nih.gov/pubmed/34401294
http://dx.doi.org/10.1016/j.rmcr.2021.101456
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author Bartimote, Christopher
Fraser-Bell, Samantha
Dunn, Hamish
author_facet Bartimote, Christopher
Fraser-Bell, Samantha
Dunn, Hamish
author_sort Bartimote, Christopher
collection PubMed
description INTRODUCTION: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have serious consequences if missed. CASE REPORT: An immunocompetent 26-year-old Filipino man living in regional Australia who was diagnosed with active pulmonary tuberculosis and started on antitubercular therapy. He was referred to an ophthalmologist for baseline ethambutol screening to exclude pre-existing optic neuropathy. Despite having no visual symptoms, when examined, the patient had vision threatening occlusive retinal vasculitis. He was initially commenced on localised therapy via bevacizumab intravitreal injections and retinal photocoagulation. Following completion of antitubercular therapy, high dose prednisone was commenced and slowly tapered. CONCLUSIONS: We present the case of an asymptomatic sight threatening occlusive vasculitis that was discovered on pre-treatment ophthalmology review. This case emphasises the need for referral for full ophthalmic screening in newly diagnosed tuberculosis to exclude vision-threatening complications.
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spelling pubmed-83490802021-08-15 Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis Bartimote, Christopher Fraser-Bell, Samantha Dunn, Hamish Respir Med Case Rep Case Report INTRODUCTION: Worldwide, tuberculosis is the leading cause of death from an infectious disease. Ocular involvement can cause significant and permanent vision loss. Ocular manifestations of tuberculosis often present with visual symptoms. Asymptomatic ocular tuberculosis is uncommon and yet can have serious consequences if missed. CASE REPORT: An immunocompetent 26-year-old Filipino man living in regional Australia who was diagnosed with active pulmonary tuberculosis and started on antitubercular therapy. He was referred to an ophthalmologist for baseline ethambutol screening to exclude pre-existing optic neuropathy. Despite having no visual symptoms, when examined, the patient had vision threatening occlusive retinal vasculitis. He was initially commenced on localised therapy via bevacizumab intravitreal injections and retinal photocoagulation. Following completion of antitubercular therapy, high dose prednisone was commenced and slowly tapered. CONCLUSIONS: We present the case of an asymptomatic sight threatening occlusive vasculitis that was discovered on pre-treatment ophthalmology review. This case emphasises the need for referral for full ophthalmic screening in newly diagnosed tuberculosis to exclude vision-threatening complications. Elsevier 2021-06-24 /pmc/articles/PMC8349080/ /pubmed/34401294 http://dx.doi.org/10.1016/j.rmcr.2021.101456 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bartimote, Christopher
Fraser-Bell, Samantha
Dunn, Hamish
Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_full Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_fullStr Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_full_unstemmed Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_short Asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
title_sort asymptomatic occlusive retinal vasculitis in newly diagnosed active tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349080/
https://www.ncbi.nlm.nih.gov/pubmed/34401294
http://dx.doi.org/10.1016/j.rmcr.2021.101456
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