Aldehyde dehydrogenase 2 alleviates monosodium iodoacetate-induced oxidative stress, inflammation and apoptosis in chondrocytes via inhibiting aquaporin 4 expression

BACKGROUND: Knee osteoarthritis (KOA) is a common cause of disability among the elderly. We aimed to explore the effects of aldehyde dehydrogenase (ALDH) 2 on the progression of KOA and identifying the potential mechanisms. METHODS: First, ALDH2 expression in knee joint effusion of patients with KOA...

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Detalles Bibliográficos
Autores principales: Pan, Lingxiao, Ding, Wei, Li, Jie, Gan, Kaifeng, Shen, Yandong, Xu, Junxiang, Zheng, Minzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349086/
https://www.ncbi.nlm.nih.gov/pubmed/34362382
http://dx.doi.org/10.1186/s12938-021-00917-0

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