Cargando…
Cognitive Impairment in Opium Use Disorder
This cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Te...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349248/ https://www.ncbi.nlm.nih.gov/pubmed/34373762 http://dx.doi.org/10.1155/2021/5548623 |
_version_ | 1783735527281786880 |
---|---|
author | Sanjari Moghaddam, Hossein Shadloo, Behrang Shahkhah, Helen Tafakhori, Abbas Haghshomar, Maryam Meshkat, Shakila Aghamollaii, Vajiheh |
author_facet | Sanjari Moghaddam, Hossein Shadloo, Behrang Shahkhah, Helen Tafakhori, Abbas Haghshomar, Maryam Meshkat, Shakila Aghamollaii, Vajiheh |
author_sort | Sanjari Moghaddam, Hossein |
collection | PubMed |
description | This cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Test-Revised (AVLT-R), Brief Visuospatial Memory Test-Revised (BVMT-R), Digit Forward and Backward Tests (DFT and DBT), and WAIS-R Digit Symbol Substitution Test (DSST). The most affected cognitive functions in patients with OUD were detected by DBT and DSST. However, we found no significant difference between patients according to the route of administration. Within patients with OUD, DBT score was associated with opium use quantity (OUQ) (r = −0.385), and DBT (r = 0.483) and DSST (r = 0.542) scores were correlated with duration of use. Our findings indicated that working memory and information-processing speed are the most affected domains of cognitive functioning. DBT and DSST could be used as brief assessments in clinical settings to screen for cognitive deficits in patients with OUD. |
format | Online Article Text |
id | pubmed-8349248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-83492482021-08-08 Cognitive Impairment in Opium Use Disorder Sanjari Moghaddam, Hossein Shadloo, Behrang Shahkhah, Helen Tafakhori, Abbas Haghshomar, Maryam Meshkat, Shakila Aghamollaii, Vajiheh Behav Neurol Research Article This cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Test-Revised (AVLT-R), Brief Visuospatial Memory Test-Revised (BVMT-R), Digit Forward and Backward Tests (DFT and DBT), and WAIS-R Digit Symbol Substitution Test (DSST). The most affected cognitive functions in patients with OUD were detected by DBT and DSST. However, we found no significant difference between patients according to the route of administration. Within patients with OUD, DBT score was associated with opium use quantity (OUQ) (r = −0.385), and DBT (r = 0.483) and DSST (r = 0.542) scores were correlated with duration of use. Our findings indicated that working memory and information-processing speed are the most affected domains of cognitive functioning. DBT and DSST could be used as brief assessments in clinical settings to screen for cognitive deficits in patients with OUD. Hindawi 2021-07-30 /pmc/articles/PMC8349248/ /pubmed/34373762 http://dx.doi.org/10.1155/2021/5548623 Text en Copyright © 2021 Hossein Sanjari Moghaddam et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Sanjari Moghaddam, Hossein Shadloo, Behrang Shahkhah, Helen Tafakhori, Abbas Haghshomar, Maryam Meshkat, Shakila Aghamollaii, Vajiheh Cognitive Impairment in Opium Use Disorder |
title | Cognitive Impairment in Opium Use Disorder |
title_full | Cognitive Impairment in Opium Use Disorder |
title_fullStr | Cognitive Impairment in Opium Use Disorder |
title_full_unstemmed | Cognitive Impairment in Opium Use Disorder |
title_short | Cognitive Impairment in Opium Use Disorder |
title_sort | cognitive impairment in opium use disorder |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349248/ https://www.ncbi.nlm.nih.gov/pubmed/34373762 http://dx.doi.org/10.1155/2021/5548623 |
work_keys_str_mv | AT sanjarimoghaddamhossein cognitiveimpairmentinopiumusedisorder AT shadloobehrang cognitiveimpairmentinopiumusedisorder AT shahkhahhelen cognitiveimpairmentinopiumusedisorder AT tafakhoriabbas cognitiveimpairmentinopiumusedisorder AT haghshomarmaryam cognitiveimpairmentinopiumusedisorder AT meshkatshakila cognitiveimpairmentinopiumusedisorder AT aghamollaiivajiheh cognitiveimpairmentinopiumusedisorder |