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κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca(2+)-SERCA2a

OBJECTIVES: We aimed to observe the protective effect of κ opioid receptor (κ-OR) agonist on myocardial injury in heart failure (HF) rats and its effect on Ca(2+)-SERCA2a and to explore the regulatory mechanism with the Nrf2/HO-1 signaling pathway. METHODS: 50 Sprague-Dawley rats were randomly divid...

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Detalles Bibliográficos
Autores principales:	Wu, Tengfei, Yao, Hui, Zhang, Binghua, Zhou, Shenglai, Hou, Ping, Chen, Keyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349291/ https://www.ncbi.nlm.nih.gov/pubmed/34373768 http://dx.doi.org/10.1155/2021/7328437

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