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The Suppression of Pin1-Alleviated Oxidative Stress through the p38 MAPK Pathway in Ischemia- and Reperfusion-Induced Acute Kidney Injury

BACKGROUND: Pin1, as the peptidyl-prolyl isomerase, plays a vital role in cellular processes. However, whether it has a regulatory effect on renal ischemia and reperfusion (I/R) injury still remains unknown. METHODS: The hypoxia/reoxygenation (H/R) model in human kidney (HK-2) cells and the I/R mode...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiaojie, Wang, Dan, Wan, Shanshan, Liu, Xiuheng, Wang, Wei, Wang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349297/ https://www.ncbi.nlm.nih.gov/pubmed/34373763 http://dx.doi.org/10.1155/2021/1313847

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