Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders

To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and...

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Detalles Bibliográficos
Autores principales: Jokiranta-Olkoniemi, Elina, Gyllenberg, David, Sucksdorff, Dan, Suominen, Auli, Kronström, Kim, Chudal, Roshan, Sourander, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349316/
https://www.ncbi.nlm.nih.gov/pubmed/33140146
http://dx.doi.org/10.1007/s10803-020-04768-x
Descripción
Sumario:To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-020-04768-x) contains supplementary material, which is available to authorized users.

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