Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders

To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and...

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Autores principales: Jokiranta-Olkoniemi, Elina, Gyllenberg, David, Sucksdorff, Dan, Suominen, Auli, Kronström, Kim, Chudal, Roshan, Sourander, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349316/
https://www.ncbi.nlm.nih.gov/pubmed/33140146
http://dx.doi.org/10.1007/s10803-020-04768-x
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author Jokiranta-Olkoniemi, Elina
Gyllenberg, David
Sucksdorff, Dan
Suominen, Auli
Kronström, Kim
Chudal, Roshan
Sourander, Andre
author_facet Jokiranta-Olkoniemi, Elina
Gyllenberg, David
Sucksdorff, Dan
Suominen, Auli
Kronström, Kim
Chudal, Roshan
Sourander, Andre
author_sort Jokiranta-Olkoniemi, Elina
collection PubMed
description To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-020-04768-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-83493162021-08-20 Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders Jokiranta-Olkoniemi, Elina Gyllenberg, David Sucksdorff, Dan Suominen, Auli Kronström, Kim Chudal, Roshan Sourander, Andre J Autism Dev Disord Original Paper To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987–2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD subjects was elevated only for natural cause of death. The risk for intentional self-harm was increased in the unadjusted analyses, but decreased to non-significant after adjusting for comorbid psychiatric disorders. ASD subjects are at increased risk for premature mortality due to natural causes of death. While ASD subjects die of suicide and present with more self-harm, the association is explained by comorbid psychiatric disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-020-04768-x) contains supplementary material, which is available to authorized users. Springer US 2020-11-02 2021 /pmc/articles/PMC8349316/ /pubmed/33140146 http://dx.doi.org/10.1007/s10803-020-04768-x Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Jokiranta-Olkoniemi, Elina
Gyllenberg, David
Sucksdorff, Dan
Suominen, Auli
Kronström, Kim
Chudal, Roshan
Sourander, Andre
Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title_full Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title_fullStr Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title_full_unstemmed Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title_short Risk for Premature Mortality and Intentional Self-harm in Autism Spectrum Disorders
title_sort risk for premature mortality and intentional self-harm in autism spectrum disorders
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349316/
https://www.ncbi.nlm.nih.gov/pubmed/33140146
http://dx.doi.org/10.1007/s10803-020-04768-x
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