Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature

Massive vaccination against COVID-19 has become a global priority. Simultaneously, concerns regarding the safety of vaccines are growing. We describe two patients who developed sensory Guillain-Barre syndrome (GBS) shortly after the first dose of the ChAdOx1 vaccine. We also summarize 12 published c...

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Detalles Bibliográficos
Autores principales: Min, Young Gi, Ju, Woohee, Ha, Ye-Eun, Ban, Jae-Jun, Lee, Seol Ah, Sung, Jung-Joon, Shin, Je-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349403/
https://www.ncbi.nlm.nih.gov/pubmed/34416410
http://dx.doi.org/10.1016/j.jneuroim.2021.577691
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author Min, Young Gi
Ju, Woohee
Ha, Ye-Eun
Ban, Jae-Jun
Lee, Seol Ah
Sung, Jung-Joon
Shin, Je-Young
author_facet Min, Young Gi
Ju, Woohee
Ha, Ye-Eun
Ban, Jae-Jun
Lee, Seol Ah
Sung, Jung-Joon
Shin, Je-Young
author_sort Min, Young Gi
collection PubMed
description Massive vaccination against COVID-19 has become a global priority. Simultaneously, concerns regarding the safety of vaccines are growing. We describe two patients who developed sensory Guillain-Barre syndrome (GBS) shortly after the first dose of the ChAdOx1 vaccine. We also summarize 12 published cases of GBS after ChAdOx1 vaccination, highlighting their unique clinical and paraclinical features. We propose a possible association between the risk of GBS and the ChAdOx1 vaccine and recommend surveillance for GBS following vaccination. Population-based studies are needed to determine causality and whether specific subpopulations are susceptible.
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spelling pubmed-83494032021-08-09 Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature Min, Young Gi Ju, Woohee Ha, Ye-Eun Ban, Jae-Jun Lee, Seol Ah Sung, Jung-Joon Shin, Je-Young J Neuroimmunol Short Communication Massive vaccination against COVID-19 has become a global priority. Simultaneously, concerns regarding the safety of vaccines are growing. We describe two patients who developed sensory Guillain-Barre syndrome (GBS) shortly after the first dose of the ChAdOx1 vaccine. We also summarize 12 published cases of GBS after ChAdOx1 vaccination, highlighting their unique clinical and paraclinical features. We propose a possible association between the risk of GBS and the ChAdOx1 vaccine and recommend surveillance for GBS following vaccination. Population-based studies are needed to determine causality and whether specific subpopulations are susceptible. Elsevier B.V. 2021-10-15 2021-08-08 /pmc/articles/PMC8349403/ /pubmed/34416410 http://dx.doi.org/10.1016/j.jneuroim.2021.577691 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Min, Young Gi
Ju, Woohee
Ha, Ye-Eun
Ban, Jae-Jun
Lee, Seol Ah
Sung, Jung-Joon
Shin, Je-Young
Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title_full Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title_fullStr Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title_full_unstemmed Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title_short Sensory Guillain-Barre syndrome following the ChAdOx1 nCov-19 vaccine: Report of two cases and review of literature
title_sort sensory guillain-barre syndrome following the chadox1 ncov-19 vaccine: report of two cases and review of literature
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349403/
https://www.ncbi.nlm.nih.gov/pubmed/34416410
http://dx.doi.org/10.1016/j.jneuroim.2021.577691
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