Cargando…

Molecular docking studies of HIV TAT and sitagliptin nano-formula as potential therapeutic targeting SARS-CoV2 protease

The outbreak of COVID-19 pandemic regarded as a major health/economic hazard. The importance of coming up with mechanisms for preventing or treating SARS-CoV-2infection has been felt across the world. This work aimed at examining the efficiency of Sitagliptin (SIT) and human immunodeficiency virus t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asfour, Hani Z., Alhakamy, Nabil A., Eljaaly, Khalid, Alaofi, Ahmed L., Tantawy, Mohamed A., Hussein, Khulood S., Aldarmahi, Ahmed A., Elfaky, Mahmoud A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Indian Chemical Society. Published by Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349443/ http://dx.doi.org/10.1016/j.jics.2021.100119

Ejemplares similares

503. In vitro Evaluation of Sitagliptin-HIV-1 Trans-activator Transcription Peptide Nano-formula for Antiviral Activity Against SARS-CoV-2: Drug Repurposing Approach
por: Eljaaly, Khalid, et al.
Publicado: (2021)

Repurposing of Sitagliptin- Melittin Optimized Nanoformula against SARS-CoV-2; Antiviral Screening and Molecular Docking Studies
por: Al-Rabia, Mohammed W., et al.
Publicado: (2021)

Evaluation of the Antiviral Activity of Sitagliptin-Glatiramer Acetate Nano-Conjugates against SARS-CoV-2 Virus
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for Nose-to-Brain Delivery
por: Md, Shadab, et al.
Publicado: (2019)

Phyto-Phospholipid Conjugated Scorpion Venom Nanovesicles as Promising Carrier That Improves Efficacy of Thymoquinone against Adenocarcinoma Human Alveolar Basal Epithelial Cells
por: Asfour, Hani Z., et al.
Publicado: (2021)

Synthetic bulky NS4A peptide variants bind to and inhibit HCV NS3 protease
por: El-Araby, Moustafa E., et al.
Publicado: (2020)

1H-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease
por: Omar, Abdelsattar M., et al.
Publicado: (2020)

Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus †
por: Alahdal, Abdulrahman M., et al.
Publicado: (2018)

Deep Ensemble Model for COVID-19 Diagnosis and Classification Using Chest CT Images
por: Ragab, Mahmoud, et al.
Publicado: (2021)

Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates
por: Badr-Eldin, Shaimaa M., et al.
Publicado: (2021)

Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Sitagliptin ameliorates the progression of atherosclerosis via down regulation of the inflammatory and oxidative pathways
por: Majeed, Sahar A, et al.
Publicado: (2013)

Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells
por: Al-Wahaibi, Lamya H., et al.
Publicado: (2020)

Substrate-gated docking of pore subunit Tha4 in the TatC cavity initiates Tat translocase assembly
por: Aldridge, Cassie, et al.
Publicado: (2014)

Large-Scale Production of Bioactive Terrein by Aspergillus terreus Strain S020 Isolated from the Saudi Coast of the Red Sea
por: Asfour, Hani Z., et al.
Publicado: (2019)

Repurposing of Some Natural Product Isolates as SARS-COV-2 Main Protease Inhibitors via In Vitro Cell Free and Cell-Based Antiviral Assessments and Molecular Modeling Approaches
por: Abdallah, Hossam M., et al.
Publicado: (2021)

Molecular docking and dynamics simulation of main protease of SARS-CoV-2 with naproxen derivative
por: K Hussein, Rageh, et al.
Publicado: (2023)

Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Muting Bacterial Communication: Evaluation of Prazosin Anti-Quorum Sensing Activities against Gram-Negative Bacteria Pseudomonas aeruginosa, Proteus mirabilis, and Serratia marcescens
por: Thabit, Abrar K., et al.
Publicado: (2022)

Silencing of Salmonella typhimurium Pathogenesis: Atenolol Acquires Efficient Anti-Virulence Activities
por: Thabit, Abrar K., et al.
Publicado: (2022)

Controlling of Bacterial Virulence: Evaluation of Anti-Virulence Activities of Prazosin against Salmonella enterica
por: Elfaky, Mahmoud A., et al.
Publicado: (2022)

Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats
por: Asfour, Hani Z., et al.
Publicado: (2022)

Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2020)

Processing by rhomboid protease is required for Providencia stuartii TatA to interact with TatC and to form functional homo-oligomeric complexes
por: Fritsch, Maximilian J, et al.
Publicado: (2012)

Unresponsive Intractable Chronic Headache With Sitagliptin
por: Zaghloul, Ahmed, et al.
Publicado: (2018)

Attitudes toward the SARS-CoV-2 Vaccine: Results from the Saudi Residents’ Intention to Get Vaccinated against COVID-19 (SRIGVAC) Study
por: Alzahrani, Sami H., et al.
Publicado: (2021)

Enhanced healing efficacy of an optimized gabapentin-melittin nanoconjugate gel-loaded formulation in excised wounds of diabetic rats
por: Asfour, Hani Z., et al.
Publicado: (2022)

In Silico-Based Discovery of Natural Anthraquinones with Potential against Multidrug-Resistant E. coli
por: Alhadrami, Hani A., et al.
Publicado: (2022)

Scaffold Hopping of α-Rubromycin Enables Direct Access to FDA-Approved Cromoglicic Acid as a SARS-CoV-2 M(Pro) Inhibitor
por: Alhadrami, Hani A., et al.
Publicado: (2021)

Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment
por: Aldawsari, Hibah M., et al.
Publicado: (2021)

Synthesis and Molecular Docking Study of Novel Pyrimidine Derivatives against COVID-19
por: Alamshany, Zahra M., et al.
Publicado: (2023)

Sitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats
por: Sharma, Ashish Kumar, et al.
Publicado: (2012)

Neurological complications of bariatric surgery
por: Algahtani, Hussein A., et al.
Publicado: (2016)

Establishment and characterization of female reproductive tract epithelial cell culture
por: Aldarmahi, Ahmed
Publicado: (2017)

Chitosan-Based Microparticles Enhance Ellagic Acid’s Colon Targeting and Proapoptotic Activity
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Phytochemical-Based Nano-Pharmacotherapeutics for Management of Burn Wound Healing
por: Qadir, Abdul, et al.
Publicado: (2021)

An Efficient Greener Approach for N-acylation of Amines in Water Using Benzotriazole Chemistry
por: Ibrahim, Tarek S., et al.
Publicado: (2020)

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways
por: Alaofi, Ahmed L.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v2cmkc1jea0qnqlrq6n88nf160