Cargando…

Adaptive immune responses to SARS-CoV-2 in recovered severe COVID-19 patients

BACKGROUND: There is an imperative need to determine the durability of adaptive immunity to SARS-CoV-2. We enumerated SARS-CoV-2-reactive CD4(+) and CD8(+) T cells targeting S1 and M proteins and measured RBD-specific serum IgG over a period of 2–6 months after symptoms onset in a cohort of subjects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olea, Beatriz, Albert, Eliseo, Torres, Ignacio, Amat, Paula, Remigia, María José, Gozalbo-Rovira, Roberto, Rodríguez-Díaz, Jesús, Buesa, Javier, Blasco, María Luisa, Redón, Josep, Signes-Costa, Jaime, Navarro, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349475/ https://www.ncbi.nlm.nih.gov/pubmed/34391981 http://dx.doi.org/10.1016/j.jcv.2021.104943

Ejemplares similares

SARS-CoV-2-reactive IFN-γ-producing CD4(+) and CD8(+) T cells in blood do not correlate with clinical severity in unvaccinated critically ill COVID-19 patients
por: Olea, Beatriz, et al.
Publicado: (2022)

SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients
por: Gozalbo-Rovira, Roberto, et al.
Publicado: (2020)

Lower respiratory tract and plasma SARS-CoV-2 RNA load in critically ill adult COVID-19 patients: Relationship with biomarkers of disease severity
por: Olea, Beatriz, et al.
Publicado: (2021)

B- and T-cell immune responses elicited by the Comirnaty® COVID-19 vaccine in nursing-home residents
por: Torres, Ignacio, et al.
Publicado: (2021)

Combined kinetic analysis of SARS-CoV-2 RNAemia, N-antigenemia and virus-specific antibodies in critically ill adult COVID-19 patients
por: Costa, Rosa, et al.
Publicado: (2022)

Evolution of SARS-CoV-2 immune responses in nursing home residents following full dose of the Comirnaty® COVID-19 vaccine
por: Giménez, Estela, et al.
Publicado: (2022)

Inference of SARS-CoV-2 spike-binding neutralizing antibody titers in sera from hospitalized COVID-19 patients by using commercial enzyme and chemiluminescent immunoassays
por: Valdivia, Arantxa, et al.
Publicado: (2021)

Initial SARS-CoV-2 RNA load in nasopharyngeal specimens is not associated with severity and midterm resolution of pneumonia in COVID-19 patients
por: Costa, Rosa, et al.
Publicado: (2022)

The Rotavirus Vaccine Landscape, an Update
por: Cárcamo-Calvo, Roberto, et al.
Publicado: (2021)

The Biofire® Filmarray® Pneumonia Plus panel for management of lower respiratory tract infection in mechanically-ventilated patients in the COVID-19 era: a diagnostic and cost-benefit evaluation
por: Ferrer, Josep, et al.
Publicado: (2023)

The Role of Host Glycobiology and Gut Microbiota in Rotavirus and Norovirus Infection, an Update
por: Peña-Gil, Nazaret, et al.
Publicado: (2021)

Relevance of secretor status genotype and microbiota composition in susceptibility to rotavirus and norovirus infections in humans
por: Rodríguez-Díaz, Jesús, et al.
Publicado: (2017)

Sero-epidemiological study of the rotavirus VP8* protein from different P genotypes in Valencia, Spain
por: Vila-Vicent, Susana, et al.
Publicado: (2020)

Recombinant Noroviruses Circulating in Spain from 2016 to 2020 and Proposal of Two Novel Genotypes within Genogroup I
por: Navarro-Lleó, Noemi, et al.
Publicado: (2022)

Monitoring of Torque Teno virus DNAemia in critically ill COVID-19 patients: May it help to predict clinical outcomes?
por: Forqué, Lorena, et al.
Publicado: (2022)

RNA viral loads of SARS-CoV-2 Alpha and Delta variants in nasopharyngeal specimens at diagnosis stratified by age, clinical presentation and vaccination status
por: Costa, Rosa, et al.
Publicado: (2022)

Replication of Human Norovirus in Mice after Antibiotic-Mediated Intestinal Bacteria Depletion
por: Santiso-Bellón, Cristina, et al.
Publicado: (2022)

Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens
por: Gozalbo-Rovira, Roberto, et al.
Publicado: (2019)

Microbiota Depletion Promotes Human Rotavirus Replication in an Adult Mouse Model
por: Gozalbo-Rovira, Roberto, et al.
Publicado: (2021)

In vitro assessment of the combined effect of letermovir and sirolimus on cytomegalovirus replication
por: Giménez, Estela, et al.
Publicado: (2023)

Epidemiological Surveillance of Norovirus and Rotavirus in Sewage (2016–2017) in Valencia (Spain)
por: Santiso-Bellón, Cristina, et al.
Publicado: (2020)

Interaction of Intestinal Bacteria with Human Rotavirus during Infection in Children
por: Gozalbo-Rovira, Roberto, et al.
Publicado: (2021)

Sample Treatment with Trypsin for RT-LAMP COVID-19 Diagnosis
por: García-Sorribes, Soraya, et al.
Publicado: (2023)

A performance comparison of two (electro) chemiluminescence immunoassays for detection and quantitation of serum anti‐spike antibodies according to SARS‐CoV‐2 vaccination and infections status
por: Camacho, Jorge, et al.
Publicado: (2022)

BD MAX Enteric Bacterial, Bacterial Plus, and Virus Panels for Diagnosis of Acute Infectious Gastroenteritis: a Cost-Benefit Analysis
por: Ferrer, Josep, et al.
Publicado: (2022)

SARS‐CoV‐2 RNA load in nasopharyngeal specimens from outpatients with breakthrough COVID‐19 due to Omicron BA.1 and BA.2
por: de Michelena, Paula, et al.
Publicado: (2022)

Performance of a flow cytometry-based immunoassay for detection of antibodies binding to SARS-CoV-2 spike protein
por: Valdivia, Arantxa, et al.
Publicado: (2022)

Nearly Complete Genome Sequences of Human Norovirus Belonging to Several Genotypes from Valencia, Spain
por: Santiso-Bellón, Cristina, et al.
Publicado: (2019)

Tracheostomy in patients with COVID-19: predictors and clinical features
por: Sancho, Jesus, et al.
Publicado: (2021)

Nearly Complete Genome Sequence of a Human Norovirus GII.P17-GII.17 Strain Isolated from Brazil in 2015
por: Santiso-Bellón, Cristina, et al.
Publicado: (2019)

Diagnostic significance of SARS-CoV-2 IgM positive/IgG negative antibody profile in symptomatic patients with suspected COVID-19 testing negative by RT-PCR
por: Valdivia, Arantxa, et al.
Publicado: (2021)

Idiopathic Pulmonary Fibrosis and Telomeres
por: Mulet, Alba, et al.
Publicado: (2022)

RNA loads of severe acute respiratory syndrome coronavirus 2 in patients with breakthrough coronavirus disease 2019 caused by the Delta and Omicron variants
por: de Michelena, Paula, et al.
Publicado: (2023)

Lung Fibrosis and Fibrosis in the Lungs: Is It All about Myofibroblasts?
por: Ortiz-Zapater, Elena, et al.
Publicado: (2022)

Impact of time elapsed since full vaccination on SARS-CoV-2 RNA load in Delta-variant breakthrough COVID-19
por: de Michelena, Paula, et al.
Publicado: (2022)

Unique Microbial Catabolic Pathway for the Human Core N-Glycan Constituent Fucosyl-α-1,6-N-Acetylglucosamine-Asparagine
por: Becerra, Jimmy E., et al.
Publicado: (2020)

Infant gut microbiota modulation by human milk disaccharides in humanized microbiome mice
por: Rubio-Del-Campo, Antonio, et al.
Publicado: (2021)

Case Report: emergent percutaneous directional thrombectomy in a patient with cardiogenic shock and large mobile thrombus in the right atrium
por: Blasco-Turrión, Sara, et al.
Publicado: (2023)

Evaluation of a rapid antigen test (Panbio™ COVID-19 Ag rapid test device) for SARS-CoV-2 detection in asymptomatic close contacts of COVID-19 patients
por: Torres, Ignacio, et al.
Publicado: (2021)

Performance comparison of a flow cytometry immunoassay for intracellular cytokine staining and the QuantiFERON® SARS-CoV-2 test for detection and quantification of SARS-CoV-2-Spike-reactive-IFN-γ-producing T cells after COVID-19 vaccination
por: Tormo, Nuria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5kchfu5qgo431tvn0hi013esah