Continuous expression of reprogramming factors induces and maintains mouse pluripotency without specific growth factors and signaling inhibitors

OBJECTIVES: Derivation and maintenance of pluripotent stem cells (PSCs) generally require optimized and complex culture media, which hinders the derivation of PSCs from various species. Expression of Oct4, Sox2, Klf4, and c‐Myc (OSKM) can reprogram somatic cells into induced PSCs (iPSCs), even for s...

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Detalles Bibliográficos
Autores principales: Mao, Yihuan, Wang, Libin, Zhong, Bei, Yang, Ning, Li, Zhikun, Cui, Tongtong, Feng, Guihai, Li, Wei, Zhang, Ying, Zhou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349648/
https://www.ncbi.nlm.nih.gov/pubmed/34197016
http://dx.doi.org/10.1111/cpr.13090

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