Cargando…

Partial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson’s disease

OBJECTIVES: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive and selective degeneration of dopaminergic neurons. Microglial activation and neuroinflammation are associated with the pathogenesis of PD. However, the relationship between microglial a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qing, Shen, Chenye, Liu, Zhaolin, Ma, Yuanyuan, Wang, Jinghui, Dong, Hongtian, Zhang, Xiaoshuang, Wang, Zishan, Yu, Mei, Ci, Lei, Sun, Ruilin, Shen, Ruling, Fei, Jian, Huang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349650/ https://www.ncbi.nlm.nih.gov/pubmed/34312932 http://dx.doi.org/10.1111/cpr.13094

Ejemplares similares

Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson’s disease mice
por: Bai, Xiaochen, et al.
Publicado: (2021)

Dynamics of spinal microglia repopulation following an acute depletion
por: Yao, Yao, et al.
Publicado: (2016)

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
por: Yang, Xiaoxia, et al.
Publicado: (2018)

NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson’s disease models
por: Liu, Zhaolin, et al.
Publicado: (2023)

Brain-specific NRSF deficiency aggravates dopaminergic neurodegeneration and impairs neurogenesis in the MPTP mouse model of Parkinson’s disease
por: Huang, Dongping, et al.
Publicado: (2019)

Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice
por: Willis, Emily F., et al.
Publicado: (2020)

Pro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models
por: Wang, Zishan, et al.
Publicado: (2020)

B cells: deplete, repopulate, vaccinate
por: Phillips, Robert
Publicado: (2022)

Dynamic Changes in the Nigrostriatal Pathway in the MPTP Mouse Model of Parkinson's Disease
por: Huang, Dongping, et al.
Publicado: (2017)

Dual extra-retinal origins of microglia in the model of retinal microglia repopulation
por: Huang, Yubin, et al.
Publicado: (2018)

Central nervous system regeneration is driven by microglia necroptosis and repopulation
por: Lloyd, Amy F., et al.
Publicado: (2019)

Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer
por: Verma, Rashmi, et al.
Publicado: (2016)

Microglial depletion and repopulation: a new era of regenerative medicine?
por: Barnett, Alexandra M., et al.
Publicado: (2020)

Monitoring B-cell repopulation after depletion therapy in neurologic patients
por: Ellwardt, Erik, et al.
Publicado: (2018)

Partial Depletion of Peripheral M1 Macrophages Reverses Motor Deficits in MPTP-Treated Mouse by Suppressing Neuroinflammation and Dopaminergic Neurodegeneration
por: Yan, Aijuan, et al.
Publicado: (2018)

Pretreatment of caffeine leads to partial neuroprotection in MPTP model of Parkinson's disease
por: Bagga, Puneet, et al.
Publicado: (2016)

CNS Repopulation by Hematopoietic-Derived Microglia-Like Cells Corrects Progranulin deficiency
por: Colella, Pasqualina, et al.
Publicado: (2023)

Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders
por: Han, Jinming, et al.
Publicado: (2018)

Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling
por: Coleman, Leon G., et al.
Publicado: (2020)

Deficiency of miR-29a/b1 leads to premature aging and dopaminergic neuroprotection in mice
por: Bai, Xiaochen, et al.
Publicado: (2022)

Single-cell transcriptome analysis reveals the immune heterogeneity and the repopulation of microglia by Hif1α in mice after spinal cord injury
por: Wang, Jingyu, et al.
Publicado: (2022)

Restorative therapy using microglial depletion and repopulation for central nervous system injuries and diseases
por: Shi, Weipeng, et al.
Publicado: (2022)

Antibiotic-induced microbiome depletion protects against MPTP-induced dopaminergic neurotoxicity in the brain
por: Pu, Yaoyu, et al.
Publicado: (2019)

The Problem of Repopulation
Publicado: (1917)

Characterizing Newly Repopulated Microglia in the Adult Mouse: Impacts on Animal Behavior, Cell Morphology, and Neuroinflammation
por: Elmore, Monica R. P., et al.
Publicado: (2015)

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
por: Lund, Harald, et al.
Publicado: (2018)

Interleukin 4-induced neuroprotection and regulation of microglia activation as a therapeutic approach in the MPTP model of Parkinson's disease
por: Spittau, Björn
Publicado: (2017)

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease
por: García-Domínguez, Irene, et al.
Publicado: (2018)

Effect of Different MPTP Administration Intervals on Mouse Models of Parkinson's Disease
por: Ma, Yuanyuan, et al.
Publicado: (2022)

Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice
por: Cheng, Xuan, et al.
Publicado: (2023)

Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease
por: Kim, Kyung In, et al.
Publicado: (2018)

Coriandrum sativum attenuates microglia mediated neuroinflammation and MPTP-induced behavioral and oxidative changes in Parkinson’s disease mouse model
por: Koppula, Sushruta, et al.
Publicado: (2021)

Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
por: Karaahmet, Berke, et al.
Publicado: (2022)

Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson’s Disease-Lessons from Transgenic Mice
por: Machado, Venissa, et al.
Publicado: (2016)

Deletion of Calhm2 alleviates MPTP-induced Parkinson's disease pathology by inhibiting EFHD2-STAT3 signaling in microglia
por: Bo, Xuena, et al.
Publicado: (2023)

25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice
por: Dean, E. Danielle, et al.
Publicado: (2012)

Alteration of Daily and Circadian Rhythms following Dopamine Depletion in MPTP Treated Non-Human Primates
por: Fifel, Karim, et al.
Publicado: (2014)

Tail Repopulation Measurements in the PSB
por: Benedetto, Elena, et al.
Publicado: (2017)

Repopulating glioma cell lines
por: Tuma, Rabiya
Publicado: (2004)

M1 macrophage-derived exosomes synergistically enhance the anti- bladder cancer effect of gemcitabine
por: Tang, Zhiling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f27n13f36gb843fgcmft5321dp