Histone H2B ubiquitination mediated chromatin relaxation is essential for the induction of somatic cell reprogramming

OBJECTIVES: Cell reprogramming has significant impacts on their potential application in regenerative medicine. Chromatin remodelling plays a very important role in cell reprogramming, but its underlying mechanism remains poorly understood. MATERIALS AND METHODS: RNA‐seq, quantitative RT‐PCR and wes...

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Detalles Bibliográficos
Autores principales: Wang, Liying, Xu, Zhiliang, Wang, Libin, Liu, Chao, Wei, Huafang, Zhang, Ruidan, Chen, Yinghong, Wang, Lina, Liu, Wenwen, Xiao, Sai, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349662/
https://www.ncbi.nlm.nih.gov/pubmed/34155716
http://dx.doi.org/10.1111/cpr.13080

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