Presence of surfactant proteins in the uteri and placentae of pregnant mares

Immunohistochemical investigations of the expression of surfactant protein A (SP-A) and surfactant protein D (SP-D) in the uterine and placental tissues of 13 pregnant mares were performed using anti-horse monoclonal primary antibodies. Strong positive reactions for both SP-A and SP-D were observed...

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Autores principales: ARAKI, Masanari, OHTAKI, Tadatoshi, KIMURA, Junpei, HOBO, Seiji, TAYA, Kazuyoshi, TSUNODA, Nobuo, TANIYAMA, Hiroyuki, TSUMAGARI, Shigehisa, NAMBO, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Theriogenology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349814/
https://www.ncbi.nlm.nih.gov/pubmed/34135243
http://dx.doi.org/10.1292/jvms.20-0174
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author ARAKI, Masanari
OHTAKI, Tadatoshi
KIMURA, Junpei
HOBO, Seiji
TAYA, Kazuyoshi
TSUNODA, Nobuo
TANIYAMA, Hiroyuki
TSUMAGARI, Shigehisa
NAMBO, Yasuo
author_facet ARAKI, Masanari
OHTAKI, Tadatoshi
KIMURA, Junpei
HOBO, Seiji
TAYA, Kazuyoshi
TSUNODA, Nobuo
TANIYAMA, Hiroyuki
TSUMAGARI, Shigehisa
NAMBO, Yasuo
author_sort ARAKI, Masanari
collection PubMed
description Immunohistochemical investigations of the expression of surfactant protein A (SP-A) and surfactant protein D (SP-D) in the uterine and placental tissues of 13 pregnant mares were performed using anti-horse monoclonal primary antibodies. Strong positive reactions for both SP-A and SP-D were observed in the trophoblasts in the microcotyledons of the placentae at 182 to 314 days of gestation; in uterine glandular epithelial cells, faint-to-weak reactions were observed during gestation. This study describes, for the first time, the changes in the SP-A and SP-D expression levels in the endometrium of mares during gestation; the SP-A and SP-D expression levels increased after the second trimester of gestation.
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spelling pubmed-83498142021-08-12 Presence of surfactant proteins in the uteri and placentae of pregnant mares ARAKI, Masanari OHTAKI, Tadatoshi KIMURA, Junpei HOBO, Seiji TAYA, Kazuyoshi TSUNODA, Nobuo TANIYAMA, Hiroyuki TSUMAGARI, Shigehisa NAMBO, Yasuo J Vet Med Sci Theriogenology Immunohistochemical investigations of the expression of surfactant protein A (SP-A) and surfactant protein D (SP-D) in the uterine and placental tissues of 13 pregnant mares were performed using anti-horse monoclonal primary antibodies. Strong positive reactions for both SP-A and SP-D were observed in the trophoblasts in the microcotyledons of the placentae at 182 to 314 days of gestation; in uterine glandular epithelial cells, faint-to-weak reactions were observed during gestation. This study describes, for the first time, the changes in the SP-A and SP-D expression levels in the endometrium of mares during gestation; the SP-A and SP-D expression levels increased after the second trimester of gestation. The Japanese Society of Veterinary Science 2021-06-15 2021-07 /pmc/articles/PMC8349814/ /pubmed/34135243 http://dx.doi.org/10.1292/jvms.20-0174 Text en ©2021 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Theriogenology
ARAKI, Masanari
OHTAKI, Tadatoshi
KIMURA, Junpei
HOBO, Seiji
TAYA, Kazuyoshi
TSUNODA, Nobuo
TANIYAMA, Hiroyuki
TSUMAGARI, Shigehisa
NAMBO, Yasuo
Presence of surfactant proteins in the uteri and placentae of pregnant mares
title Presence of surfactant proteins in the uteri and placentae of pregnant mares
title_full Presence of surfactant proteins in the uteri and placentae of pregnant mares
title_fullStr Presence of surfactant proteins in the uteri and placentae of pregnant mares
title_full_unstemmed Presence of surfactant proteins in the uteri and placentae of pregnant mares
title_short Presence of surfactant proteins in the uteri and placentae of pregnant mares
title_sort presence of surfactant proteins in the uteri and placentae of pregnant mares
topic Theriogenology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349814/
https://www.ncbi.nlm.nih.gov/pubmed/34135243
http://dx.doi.org/10.1292/jvms.20-0174
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