Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm

The effect of lactoferrin (LF) on embryo development was investigated by using lipopolysaccharide (LPS)-treated mouse sperm. For the development rate of the 2-cell stage embryo, the embryo derived from LPS- and LF-treated sperm showed similar survival rate to the control embryo. On day 12 after the...

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Detalles Bibliográficos
Autores principales: AYA, Takahiro, TOMIOKA, Yukiko, TAKEUCHI, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Anatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349819/
https://www.ncbi.nlm.nih.gov/pubmed/34108340
http://dx.doi.org/10.1292/jvms.21-0251
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author AYA, Takahiro
TOMIOKA, Yukiko
TAKEUCHI, Takashi
author_facet AYA, Takahiro
TOMIOKA, Yukiko
TAKEUCHI, Takashi
author_sort AYA, Takahiro
collection PubMed
description The effect of lactoferrin (LF) on embryo development was investigated by using lipopolysaccharide (LPS)-treated mouse sperm. For the development rate of the 2-cell stage embryo, the embryo derived from LPS- and LF-treated sperm showed similar survival rate to the control embryo. On day 12 after the embryo transfer into the recipient, the frequent abnormality was observed in the embryo derived from LPS-treated sperm, and the abnormality was tended to be inhibited in the embryo derived from LPS- and LF-treated sperm. These results imply that LF treatment on sperm contaminated with bacteria may facilitate the embryo development, which contribute to the improvement of infertility.
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spelling pubmed-83498192021-08-12 Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm AYA, Takahiro TOMIOKA, Yukiko TAKEUCHI, Takashi J Vet Med Sci Anatomy The effect of lactoferrin (LF) on embryo development was investigated by using lipopolysaccharide (LPS)-treated mouse sperm. For the development rate of the 2-cell stage embryo, the embryo derived from LPS- and LF-treated sperm showed similar survival rate to the control embryo. On day 12 after the embryo transfer into the recipient, the frequent abnormality was observed in the embryo derived from LPS-treated sperm, and the abnormality was tended to be inhibited in the embryo derived from LPS- and LF-treated sperm. These results imply that LF treatment on sperm contaminated with bacteria may facilitate the embryo development, which contribute to the improvement of infertility. The Japanese Society of Veterinary Science 2021-06-09 2021-07 /pmc/articles/PMC8349819/ /pubmed/34108340 http://dx.doi.org/10.1292/jvms.21-0251 Text en ©2021 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Anatomy
AYA, Takahiro
TOMIOKA, Yukiko
TAKEUCHI, Takashi
Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title_full Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title_fullStr Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title_full_unstemmed Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title_short Effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
title_sort effect of lactoferrin on murine embryo development created from lipopolysaccharide-treated sperm
topic Anatomy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349819/
https://www.ncbi.nlm.nih.gov/pubmed/34108340
http://dx.doi.org/10.1292/jvms.21-0251
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AT takeuchitakashi effectoflactoferrinonmurineembryodevelopmentcreatedfromlipopolysaccharidetreatedsperm

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