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PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging

The tumor suppressor phosphatase and tensin homolog (PTEN) negatively regulates the insulin signaling pathway. Germline PTEN pathogenic variants cause PTEN hamartoma tumor syndrome (PHTS), associated with lipoma development in children. Adipose progenitor cells (APCs) lose their capacity to differen...

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Detalles Bibliográficos
Autores principales:	Kirstein, Anna S., Kehr, Stephanie, Nebe, Michèle, Hanschkow, Martha, Barth, Lisa A.G., Lorenz, Judith, Penke, Melanie, Breitfeld, Jana, Le Duc, Diana, Landgraf, Kathrin, Körner, Antje, Kovacs, Peter, Stadler, Peter F., Kiess, Wieland, Garten, Antje
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350019/ https://www.ncbi.nlm.nih.gov/pubmed/34273354 http://dx.doi.org/10.1016/j.jbc.2021.100968

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