Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment: a retrospective study

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare malignant tumor associated with asbestos exposure, with infaust prognosis and overall survival below 20 months in treated patients. Platinum is still the backbone of the chemotherapy protocols, and the reasons for the rather poor efficacy of...

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Detalles Bibliográficos
Autores principales: Mathilakathu, Alexander, Borchert, Sabrina, Wessolly, Michael, Mairinger, Elena, Beckert, Hendrik, Steinborn, Julia, Hager, Thomas, Christoph, Daniel C., Kollmeier, Jens, Wohlschlaeger, Jeremias, Mairinger, Thomas, Schmid, Kurt Werner, Walter, Robert F. H., Brcic, Luka, Mairinger, Fabian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350085/
https://www.ncbi.nlm.nih.gov/pubmed/34430345
http://dx.doi.org/10.21037/tlcr-21-201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350085/
https://www.ncbi.nlm.nih.gov/pubmed/34430345
http://dx.doi.org/10.21037/tlcr-21-201

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