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Mitogen signal-associated pathways, energy metabolism regulation, and mediation of tumor immunogenicity play essential roles in the cellular response of malignant pleural mesotheliomas to platinum-based treatment: a retrospective study
BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare malignant tumor associated with asbestos exposure, with infaust prognosis and overall survival below 20 months in treated patients. Platinum is still the backbone of the chemotherapy protocols, and the reasons for the rather poor efficacy of...
Autores principales: | Mathilakathu, Alexander, Borchert, Sabrina, Wessolly, Michael, Mairinger, Elena, Beckert, Hendrik, Steinborn, Julia, Hager, Thomas, Christoph, Daniel C., Kollmeier, Jens, Wohlschlaeger, Jeremias, Mairinger, Thomas, Schmid, Kurt Werner, Walter, Robert F. H., Brcic, Luka, Mairinger, Fabian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350085/ https://www.ncbi.nlm.nih.gov/pubmed/34430345 http://dx.doi.org/10.21037/tlcr-21-201 |
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