Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies

BACKGROUND: Although most malignancies express cancer-testis antigens (CTA), immune responses to these proteins are limited in thoracic oncology patients. This trial was undertaken to examine if a cancer cell lysate vaccine could induce immunity to CTA, and to ascertain if metronomic cyclophosphamid...

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Detalles Bibliográficos
Autores principales: Zhang, Mary, Hong, Julie A., Kunst, Tricia F., Bond, Colleen D., Kenney, Cara M., Warga, Cheryl L., Yeray, Javier, Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Miettinen, Markku, Ripley, R. Taylor, Hoang, Chuong D., Gnjatic, Sacha, Trepel, Jane B., Schrump, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350099/
https://www.ncbi.nlm.nih.gov/pubmed/34430349
http://dx.doi.org/10.21037/tlcr-21-1

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