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Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression

BACKGROUND: Spinal muscular atrophy is an inherited neurodegenerative disease caused by insufficient levels of the survival motor neuron (SMN) protein. Recently approved treatments aimed at increasing SMN protein levels have dramatically improved patient survival and have altered the disease landsca...

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Detalles Bibliográficos
Autores principales: McCormack, Nikki M., Villalón, Eric, Viollet, Coralie, Soltis, Anthony R., Dalgard, Clifton L., Lorson, Christian L., Burnett, Barrington G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350220/
https://www.ncbi.nlm.nih.gov/pubmed/34115448
http://dx.doi.org/10.1002/jcsm.12740