Cargando…
Immune-Intrinsic Myd88 Directs the Production of Antibodies With Specificity for Extracellular Matrix Components in Primary Sjögren’s Syndrome
Primary Sjögren’s syndrome is an autoimmune disease that is predominantly seen in women. The disease is characterized by exocrine gland dysfunction in combination with serious systemic manifestations. At present, the causes of pSS are poorly understood. Pulmonary and renal inflammation are observed...
Autores principales: | Kiripolsky, Jeremy, Kasperek, Eileen M., Zhu, Chengsong, Li, Quan-Zhen, Wang, Jia, Yu, Guan, Kramer, Jill M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350326/ https://www.ncbi.nlm.nih.gov/pubmed/34381449 http://dx.doi.org/10.3389/fimmu.2021.692216 |
Ejemplares similares
-
Activation of Myd88-Dependent TLRs Mediates Local and Systemic Inflammation in a Mouse Model of Primary Sjögren's Syndrome
por: Kiripolsky, Jeremy, et al.
Publicado: (2020) -
TLR7 agonism accelerates disease in a mouse model of primary Sjögren’s syndrome and drives expansion of T-bet(+) B cells
por: Punnanitinont, Achamaporn, et al.
Publicado: (2022) -
Current and Emerging Evidence for Toll-Like Receptor Activation in Sjögren's Syndrome
por: Kiripolsky, Jeremy, et al.
Publicado: (2018) -
Myd88 Is Required for an Antibody Response to Retroviral Infection
por: Browne, Edward P., et al.
Publicado: (2009) -
SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas
por: Munshi, Manit, et al.
Publicado: (2020)