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A GSK3-SRF Axis Mediates Angiotensin II Induced Endothelin Transcription in Vascular Endothelial Cells

Endothelin, encoded by ET1, is a vasoactive substance primarily synthesized in vascular endothelial cells (VECs). Elevation of endothelin levels, due to transcriptional hyperactivation, has been observed in a host of cardiovascular diseases. We have previously shown that serum response factor (SRF)...

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Detalles Bibliográficos
Autores principales:	Yang, Yuyu, Wang, Huidi, Zhao, Hongwei, Miao, Xiulian, Guo, Yan, Zhuo, Lili, Xu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350349/ https://www.ncbi.nlm.nih.gov/pubmed/34381779 http://dx.doi.org/10.3389/fcell.2021.698254

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