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ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts

Bone homeostasis is a metabolic balance between the new bone formation by osteoblasts and old bone resorption by osteoclasts. Excessive osteoclastic bone resorption results in low bone mass, which is the major cause of bone diseases such as rheumatoid arthritis. Small GTPases Rac1 is a key regulator...

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Detalles Bibliográficos
Autores principales: Liang, Xinyue, Hou, Yafei, Han, Lijuan, Yu, Shuxiang, Zhang, Yunyun, Cao, Xiumei, Yan, Jianshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350380/
https://www.ncbi.nlm.nih.gov/pubmed/34381782
http://dx.doi.org/10.3389/fcell.2021.702916