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Binding to PI(4,5)P(2) is indispensable for secretion of B-cell clonogenic HIV-1 matrix protein p17 variants

HIV-1 matrix protein p17 variants (vp17s) derived from non-Hodgkin's lymphoma (NHL) tissues of HIV-1–seropositive (HIV(+)) patients promote B-cell growth by activating the Akt signaling pathway. It is fundamental to understand the role played by vp17s in producing a microenvironment that foster...

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Detalles Bibliográficos
Autores principales: Bugatti, Antonella, Caccuri, Francesca, Filippini, Federica, Ravelli, Cosetta, Caruso, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350382/
https://www.ncbi.nlm.nih.gov/pubmed/34273353
http://dx.doi.org/10.1016/j.jbc.2021.100934

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