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BRAF Mutation as a Potential Therapeutic Target for Checkpoint Inhibitors: A Comprehensive Analysis of Immune Microenvironment in BRAF Mutated Colon Cancer

BRAF mutated colon cancer presents with poor survival, and the treatment strategies are controversial. The tumor microenvironment, which plays a key role in tumorigenesis as well as responses to treatments, of this subtype is largely unknown. In the present study, we analyzed the differences of immu...

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Detalles Bibliográficos
Autores principales: Cen, Shuyi, Liu, Kun, Zheng, Yu, Shan, Jianzhen, Jing, Chao, Gao, Jiale, Pan, Hongming, Bai, Zhigang, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350390/
https://www.ncbi.nlm.nih.gov/pubmed/34381786
http://dx.doi.org/10.3389/fcell.2021.705060