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BCR Affinity Influences T-B Interactions and B Cell Development in Secondary Lymphoid Organs

B cells produce high-affinity immunoglobulins (Igs), or antibodies, to eliminate foreign pathogens. Mature, naïve B cells expressing an antigen-specific cell surface Ig, or B cell receptor (BCR), are directed toward either an extrafollicular (EF) or germinal center (GC) response upon antigen binding...

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Detalles Bibliográficos
Autores principales:	Wishnie, Alec J., Chwat-Edelstein, Tzippora, Attaway, Mary, Vuong, Bao Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350505/ https://www.ncbi.nlm.nih.gov/pubmed/34381455 http://dx.doi.org/10.3389/fimmu.2021.703918

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