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LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations

Cell-free DNA (cfDNA) measured via liquid biopsies provides a way for minimally invasive monitoring of tumor evolutionary dynamics during therapy. Here we present liquidCNA, a method to track subclonal evolution from longitudinally collected cfDNA samples sequenced through cost-effective low-pass wh...

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Detalles Bibliográficos
Autores principales:	Lakatos, Eszter, Hockings, Helen, Mossner, Maximilian, Huang, Weini, Lockley, Michelle, Graham, Trevor A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350516/ https://www.ncbi.nlm.nih.gov/pubmed/34401670 http://dx.doi.org/10.1016/j.isci.2021.102889

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