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Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication
BACKGROUND & AIMS: In experimental models, alcohol induces acute changes in lipid metabolism that cause hepatocyte lipoapoptosis and inflammation. Here we study human hepatic lipid turnover during controlled alcohol intoxication. METHODS: We studied 39 participants with 3 distinct hepatic phenot...
Autores principales: | Israelsen, Mads, Kim, Min, Suvitaival, Tommi, Madsen, Bjørn Stæhr, Hansen, Camilla Dalby, Torp, Nikolaj, Trost, Kajetan, Thiele, Maja, Hansen, Torben, Legido-Quigley, Cristina, Krag, Aleksander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350545/ https://www.ncbi.nlm.nih.gov/pubmed/34401690 http://dx.doi.org/10.1016/j.jhepr.2021.100325 |
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