The Dual Dose-Dependent Effects of Corticosterone on Hippocampal Cell Apoptosis After Traumatic Brain Injury Depend on the Activation Ratio of Mineralocorticoid Receptors to Glucocorticoid Receptors

In our recent studies, we reported that mineralocorticoid receptor (MR) had the opposite effects of glucocorticoid receptor (GR) on neural cell survival after traumatic brain injury (TBI). However, whether short-term use of high-dose natural glucocorticoids, which are mixed agonists of both MR and G...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Yang, Mengshi, Yan, Qiongyu, Xu, Xiaojian, Niu, Fei, Dong, Jinqian, Zhuang, Yuan, Lu, Shenghua, Ge, Qianqian, Liu, Baiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350576/
https://www.ncbi.nlm.nih.gov/pubmed/34381366
http://dx.doi.org/10.3389/fphar.2021.713715

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