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METTL3-induced UCK2 m(6)A hypermethylation promotes melanoma cancer cell metastasis via the WNT/β-catenin pathway
BACKGROUND: Melanoma is a highly aggressive, malignant skin tumor with a statistically high mortality rate. N6-methyladenosine (m(6)A) modification is involved in a variety of biological processes, including tumorigenesis. m(6)A modifications regulate the fate and functions of RNA, such as mRNA stab...
Autores principales: | Wu, Hao, Xu, Haochao, Jia, Dongdong, Li, Tao, Xia, Liming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350655/ https://www.ncbi.nlm.nih.gov/pubmed/34430596 http://dx.doi.org/10.21037/atm-21-2906 |
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