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Bepridil, a class IV antiarrhythmic agent, can block the TREK-1 potassium channel

BACKGROUND: The TWIK-related potassium channel (TREK-1) can be regulated by different stimuli. However, it is not clear whether some antiarrhythmics affect the activity of TREK-1. In the present study, the effect of bepridil on the TREK-1 currents is investigated. METHODS: In a TREK-1 stably-express...

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Detalles Bibliográficos
Autores principales:	Wang, Ying, Fu, Zhijie, Ma, Zhiyong, Li, Na, Shang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350656/ https://www.ncbi.nlm.nih.gov/pubmed/34430564 http://dx.doi.org/10.21037/atm-20-7971

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