KEAP1/NFE2L2 Mutations of Liquid Biopsy as Prognostic Biomarkers in Patients With Advanced Non-Small Cell Lung Cancer: Results From Two Multicenter, Randomized Clinical Trials

PURPOSE: The KEAP1-NFE2L2 (Kelch-like ECH-associated protein 1 (KEAP1)-Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2)) mutations are associated with resistance to chemotherapy or immunotherapy in non-small cell lung cancer (NSCLC). Conversely, it has been reported that NFE2L2 mutations potenti...

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Detalles Bibliográficos
Autores principales: Zhu, Hongyuan, Xie, Daipeng, Yu, Yunfang, Yao, Lintong, Xu, Bin, Huang, Luyu, Wu, Shaowei, Li, Fasheng, Zheng, Yating, Liu, Xinyi, Xie, Wenzhuan, Huang, Mengli, Li, Hao, Zheng, Shaopeng, Zhang, Dongkun, Qiao, Guibin, Chan, Lawrence W. C., Zhou, Haiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350725/
https://www.ncbi.nlm.nih.gov/pubmed/34381706
http://dx.doi.org/10.3389/fonc.2021.659200

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