COVID-19 chez les femmes utilisant un traitement hormonal: quelles préventions?

Mortality from SARS-Cov-2 infection appears to be higher in men as compared to women. Women have a more effective, intense and prolonged immune response to both humoral (stimulated by estradiol) and cellular immunity, inducing high levels of antibodies. The expression of angiotensin II converting enzyme is stimulated by estrogen. The infection induces changes in coagulation. Hormonal treatments (combined hormonal contraception, menopausal hormonal treatment, adjuvant hormonal treatment in the context of breast cancer) modify coagulation. Recommendations from learned societies have been issued to prevent thromboembolic events in women using these hormonal treatments.