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Periscopic technique in Norwood operation is associated with better preservation of early ventricular function

OBJECTIVE: Although the right ventricle (RV) to pulmonary artery conduit in stage 1 Norwood operation results in improved interstage survival, the long-term effects of the ventriculotomy used in the traditional technique remain a concern. The periscopic technique (PT) of RV to pulmonary artery condu...

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Autores principales: Bhatla, Puneet, Kumar, TK Susheel, Makadia, Luv, Winston, Brandon, Bull, Catherine, Nielsen, James C., Williams, David, Chakravarti, Sujata, Ohye, Richard G., Mosca, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350951/
https://www.ncbi.nlm.nih.gov/pubmed/34401829
http://dx.doi.org/10.1016/j.xjtc.2021.05.014
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author Bhatla, Puneet
Kumar, TK Susheel
Makadia, Luv
Winston, Brandon
Bull, Catherine
Nielsen, James C.
Williams, David
Chakravarti, Sujata
Ohye, Richard G.
Mosca, Ralph S.
author_facet Bhatla, Puneet
Kumar, TK Susheel
Makadia, Luv
Winston, Brandon
Bull, Catherine
Nielsen, James C.
Williams, David
Chakravarti, Sujata
Ohye, Richard G.
Mosca, Ralph S.
author_sort Bhatla, Puneet
collection PubMed
description OBJECTIVE: Although the right ventricle (RV) to pulmonary artery conduit in stage 1 Norwood operation results in improved interstage survival, the long-term effects of the ventriculotomy used in the traditional technique remain a concern. The periscopic technique (PT) of RV to pulmonary artery conduit placement has been described as an alternative technique to minimize RV injury. A retrospective study was performed to compare the effects of traditional technique and PT on ventricular function following Norwood operation. METHODS: A retrospective study of all patients who underwent Norwood operation from 2012 to 2019 was performed. Patients with baseline RV dysfunction and significant tricuspid valve regurgitation were excluded. Prestage 2 echocardiograms were reviewed by a blinded experienced imager for quantification of RV function (sinus and infundibular RV fractional area change) as well as for regional conduit site wall dysfunction (normal or abnormal, including hypokinesia, akinesia, or dyskinesia). Wilcoxon rank-sum tests were used to assess differences in RV infundibular and RV sinus ejection fraction and the Fisher exact test was used to assess differences in regional wall dysfunction. RESULTS: Twenty-two patients met inclusion criteria. Eight underwent traditional technique and 14 underwent PT. Median infundibular RV fractional area change was 49% and 37% (P = .02) and sinus RV fractional area change was 50% and 41% for PT and traditional technique (P = .007) respectively. Similarly qualitative regional RV wall function was better preserved in PT (P = .002). CONCLUSIONS: The PT for RV to pulmonary artery conduit in Norwood operation results in better preservation of early RV global and regional systolic function. Whether or not this benefit translates to improved clinical outcome still needs to be studied.
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spelling pubmed-83509512021-08-15 Periscopic technique in Norwood operation is associated with better preservation of early ventricular function Bhatla, Puneet Kumar, TK Susheel Makadia, Luv Winston, Brandon Bull, Catherine Nielsen, James C. Williams, David Chakravarti, Sujata Ohye, Richard G. Mosca, Ralph S. JTCVS Tech Congenital: Norwood Procedure OBJECTIVE: Although the right ventricle (RV) to pulmonary artery conduit in stage 1 Norwood operation results in improved interstage survival, the long-term effects of the ventriculotomy used in the traditional technique remain a concern. The periscopic technique (PT) of RV to pulmonary artery conduit placement has been described as an alternative technique to minimize RV injury. A retrospective study was performed to compare the effects of traditional technique and PT on ventricular function following Norwood operation. METHODS: A retrospective study of all patients who underwent Norwood operation from 2012 to 2019 was performed. Patients with baseline RV dysfunction and significant tricuspid valve regurgitation were excluded. Prestage 2 echocardiograms were reviewed by a blinded experienced imager for quantification of RV function (sinus and infundibular RV fractional area change) as well as for regional conduit site wall dysfunction (normal or abnormal, including hypokinesia, akinesia, or dyskinesia). Wilcoxon rank-sum tests were used to assess differences in RV infundibular and RV sinus ejection fraction and the Fisher exact test was used to assess differences in regional wall dysfunction. RESULTS: Twenty-two patients met inclusion criteria. Eight underwent traditional technique and 14 underwent PT. Median infundibular RV fractional area change was 49% and 37% (P = .02) and sinus RV fractional area change was 50% and 41% for PT and traditional technique (P = .007) respectively. Similarly qualitative regional RV wall function was better preserved in PT (P = .002). CONCLUSIONS: The PT for RV to pulmonary artery conduit in Norwood operation results in better preservation of early RV global and regional systolic function. Whether or not this benefit translates to improved clinical outcome still needs to be studied. Elsevier 2021-05-21 /pmc/articles/PMC8350951/ /pubmed/34401829 http://dx.doi.org/10.1016/j.xjtc.2021.05.014 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Congenital: Norwood Procedure
Bhatla, Puneet
Kumar, TK Susheel
Makadia, Luv
Winston, Brandon
Bull, Catherine
Nielsen, James C.
Williams, David
Chakravarti, Sujata
Ohye, Richard G.
Mosca, Ralph S.
Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title_full Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title_fullStr Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title_full_unstemmed Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title_short Periscopic technique in Norwood operation is associated with better preservation of early ventricular function
title_sort periscopic technique in norwood operation is associated with better preservation of early ventricular function
topic Congenital: Norwood Procedure
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350951/
https://www.ncbi.nlm.nih.gov/pubmed/34401829
http://dx.doi.org/10.1016/j.xjtc.2021.05.014
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