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High-Precision Quantitative Analysis Reveals Carcinoembryonic Protein Expression Differs Among Colorectal Cancer Primary Foci and Metastases to Different Sites

The expression of carcinoembryonic protein (CEA) is an important biological marker and therapeutic target in colorectal cancer (CRC). CEA expression heterogeneity confers resistance to CEA-targeting immunotherapy antibodies. Thus, quantification of the CEA-positive cell ratio among all tumor cells w...

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Detalles Bibliográficos
Autores principales: Zhu, Yazhen, Zhang, Qin, Wei, Chengjiang, Hu, Ying, Gong, Han, Liu, Yi, Lai, Hao, Feng, Yan, Lin, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351024/
https://www.ncbi.nlm.nih.gov/pubmed/34342245
http://dx.doi.org/10.1177/15330338211037175