Sulforaphane attenuates cisplatin-induced hearing loss by inhibiting histone deacetylase expression

INTRODUCTION: Cruciferous vegetables are a rich source of sulforaphane (SFN), which acts as a natural HDAC inhibitor (HDACi). Our previous study found that HDACi could restore histone acetyltransferase/histone deacetylase (HAT/HDAC) balance in the cochlea and attenuate gentamicin-induced hearing los...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Tian, Ke-yong, Fang, Ying, Chang, Hui-min, Han, Ya-nan, Chen, Fu-quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351026/
https://www.ncbi.nlm.nih.gov/pubmed/34344210
http://dx.doi.org/10.1177/20587384211034086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351026/
https://www.ncbi.nlm.nih.gov/pubmed/34344210
http://dx.doi.org/10.1177/20587384211034086

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