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Infection Recurrence in Instrumented Spinal Fusion in Children

STUDY DESIGN: Level 4 retrospective case series. OBJECTIVES: Surgical site infection (SSI) is one of the main complications of instrumented spinal fusion. The aim of our study was to evaluate infection recurrence (same bacteria) or reinfection (different bacteria) in posterior spinal fusion in child...

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Autores principales: Moyano, Carlos A., Tello, Carlos A., Piantoni, Lucas, Wilson, Ida A. Francheri, Galaretto, Eduardo, Remondino, Rodrigo G., Bersusky, Ernesto, Noël, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351060/
https://www.ncbi.nlm.nih.gov/pubmed/32783471
http://dx.doi.org/10.1177/2192568220935818
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author Moyano, Carlos A.
Tello, Carlos A.
Piantoni, Lucas
Wilson, Ida A. Francheri
Galaretto, Eduardo
Remondino, Rodrigo G.
Bersusky, Ernesto
Noël, Mariano A.
author_facet Moyano, Carlos A.
Tello, Carlos A.
Piantoni, Lucas
Wilson, Ida A. Francheri
Galaretto, Eduardo
Remondino, Rodrigo G.
Bersusky, Ernesto
Noël, Mariano A.
author_sort Moyano, Carlos A.
collection PubMed
description STUDY DESIGN: Level 4 retrospective case series. OBJECTIVES: Surgical site infection (SSI) is one of the main complications of instrumented spinal fusion. The aim of our study was to evaluate infection recurrence (same bacteria) or reinfection (different bacteria) in posterior spinal fusion in children. METHODS: A retrospective study was conducted to evaluate patients who were successfully treated for SSI after instrumented spinal fusion due to deformity, with irrigation and debridement (I&D) procedures, followed by antibiotic therapy, with a follow-up of at least 2 years. RESULTS: Overall, 29 patients with a mean age of 14 + 3 years were evaluated. Preoperative diagnosis was nonidiopathic scoliosis in 23, idiopathic scoliosis in 5, and Scheuermann’s disease in 1 patient. The etiology was Gram-positive cocci (40.9%), Gram-negative bacilli (27.2%), and polymicrobial infection (31.8%). A mean of 1.5 (1-3) I&D procedures were performed. Intravenous antibiotic treatment was given for a mean of 15.8 (4-86) days, followed by oral treatment for a mean of 335.1 (0-1095) days. Mean follow-up was 5 + 2 years (2 to 14 + 7 years) during which 28 patients were cured (96.6%) and 1 patient developed reinfection (3.4%). This reinfection was treated with oral clindamycin for 6 months. After the infection persisted, the decision was to remove the implants. CONCLUSIONS: In this series of 29 pediatric patients who underwent instrumented spinal fusion due to deformity, we reported one case of reinfection (3.4%). Given that 96.6% of infections were resolved, we suggest treatment with I&D procedures with retention of implants to treat acute SSI.
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spelling pubmed-83510602021-08-13 Infection Recurrence in Instrumented Spinal Fusion in Children Moyano, Carlos A. Tello, Carlos A. Piantoni, Lucas Wilson, Ida A. Francheri Galaretto, Eduardo Remondino, Rodrigo G. Bersusky, Ernesto Noël, Mariano A. Global Spine J Original Articles STUDY DESIGN: Level 4 retrospective case series. OBJECTIVES: Surgical site infection (SSI) is one of the main complications of instrumented spinal fusion. The aim of our study was to evaluate infection recurrence (same bacteria) or reinfection (different bacteria) in posterior spinal fusion in children. METHODS: A retrospective study was conducted to evaluate patients who were successfully treated for SSI after instrumented spinal fusion due to deformity, with irrigation and debridement (I&D) procedures, followed by antibiotic therapy, with a follow-up of at least 2 years. RESULTS: Overall, 29 patients with a mean age of 14 + 3 years were evaluated. Preoperative diagnosis was nonidiopathic scoliosis in 23, idiopathic scoliosis in 5, and Scheuermann’s disease in 1 patient. The etiology was Gram-positive cocci (40.9%), Gram-negative bacilli (27.2%), and polymicrobial infection (31.8%). A mean of 1.5 (1-3) I&D procedures were performed. Intravenous antibiotic treatment was given for a mean of 15.8 (4-86) days, followed by oral treatment for a mean of 335.1 (0-1095) days. Mean follow-up was 5 + 2 years (2 to 14 + 7 years) during which 28 patients were cured (96.6%) and 1 patient developed reinfection (3.4%). This reinfection was treated with oral clindamycin for 6 months. After the infection persisted, the decision was to remove the implants. CONCLUSIONS: In this series of 29 pediatric patients who underwent instrumented spinal fusion due to deformity, we reported one case of reinfection (3.4%). Given that 96.6% of infections were resolved, we suggest treatment with I&D procedures with retention of implants to treat acute SSI. SAGE Publications 2020-08-12 2021-09 /pmc/articles/PMC8351060/ /pubmed/32783471 http://dx.doi.org/10.1177/2192568220935818 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Moyano, Carlos A.
Tello, Carlos A.
Piantoni, Lucas
Wilson, Ida A. Francheri
Galaretto, Eduardo
Remondino, Rodrigo G.
Bersusky, Ernesto
Noël, Mariano A.
Infection Recurrence in Instrumented Spinal Fusion in Children
title Infection Recurrence in Instrumented Spinal Fusion in Children
title_full Infection Recurrence in Instrumented Spinal Fusion in Children
title_fullStr Infection Recurrence in Instrumented Spinal Fusion in Children
title_full_unstemmed Infection Recurrence in Instrumented Spinal Fusion in Children
title_short Infection Recurrence in Instrumented Spinal Fusion in Children
title_sort infection recurrence in instrumented spinal fusion in children
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351060/
https://www.ncbi.nlm.nih.gov/pubmed/32783471
http://dx.doi.org/10.1177/2192568220935818
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