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Venous Thromboembolism Prophylaxis in Elective Spine Surgery

STUDY DESIGN: Review. OBJECTIVE: Venothromboembolic (VTE) complications, composed of deep vein thrombosis and pulmonary embolism are commonly observed in the perioperative setting. There are approximately 500 000 postoperative VTE cases annually in the United States and orthopedic procedures contrib...

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Autores principales: Solaru, Samantha, Alluri, Ram K., Wang, Jeffrey C., Hah, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351068/
https://www.ncbi.nlm.nih.gov/pubmed/33034229
http://dx.doi.org/10.1177/2192568220962439
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author Solaru, Samantha
Alluri, Ram K.
Wang, Jeffrey C.
Hah, Raymond J.
author_facet Solaru, Samantha
Alluri, Ram K.
Wang, Jeffrey C.
Hah, Raymond J.
author_sort Solaru, Samantha
collection PubMed
description STUDY DESIGN: Review. OBJECTIVE: Venothromboembolic (VTE) complications, composed of deep vein thrombosis and pulmonary embolism are commonly observed in the perioperative setting. There are approximately 500 000 postoperative VTE cases annually in the United States and orthopedic procedures contribute significantly to this incidence. Data on the use of VTE prophylaxis in elective spinal surgery is sparse. This review aims to provide an updated consensus within the literature defining the risk factors, diagnosis, and the safety profile of routine use of pharmacological prophylaxis for VTE in elective spine surgery patients. METHODS: A comprehensive review of the literature and compilation of findings relating to current identified risk factors for VTE, diagnostic methods, and prophylactic intervention and safety in elective spine surgery. RESULTS: VTE prophylaxis use is still widely contested in elective spine surgery patients. The outlined benefits of mechanical prophylaxis compared with chemical prophylaxis varies among practitioners. CONCLUSION: The benefits of any form of VTE prophylaxis continues to remain a controversial topic in the elective spine surgery setting. A specific set of guidelines for implementing prophylaxis is yet to be determined. As more risk factors for thromboembolic events are identified, the complexity surrounding intervention selection increases. The benefits of prophylaxis must also continue to be balanced against the increased risk of bleeding events and neurologic injury.
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spelling pubmed-83510682021-08-13 Venous Thromboembolism Prophylaxis in Elective Spine Surgery Solaru, Samantha Alluri, Ram K. Wang, Jeffrey C. Hah, Raymond J. Global Spine J Review Articles STUDY DESIGN: Review. OBJECTIVE: Venothromboembolic (VTE) complications, composed of deep vein thrombosis and pulmonary embolism are commonly observed in the perioperative setting. There are approximately 500 000 postoperative VTE cases annually in the United States and orthopedic procedures contribute significantly to this incidence. Data on the use of VTE prophylaxis in elective spinal surgery is sparse. This review aims to provide an updated consensus within the literature defining the risk factors, diagnosis, and the safety profile of routine use of pharmacological prophylaxis for VTE in elective spine surgery patients. METHODS: A comprehensive review of the literature and compilation of findings relating to current identified risk factors for VTE, diagnostic methods, and prophylactic intervention and safety in elective spine surgery. RESULTS: VTE prophylaxis use is still widely contested in elective spine surgery patients. The outlined benefits of mechanical prophylaxis compared with chemical prophylaxis varies among practitioners. CONCLUSION: The benefits of any form of VTE prophylaxis continues to remain a controversial topic in the elective spine surgery setting. A specific set of guidelines for implementing prophylaxis is yet to be determined. As more risk factors for thromboembolic events are identified, the complexity surrounding intervention selection increases. The benefits of prophylaxis must also continue to be balanced against the increased risk of bleeding events and neurologic injury. SAGE Publications 2020-10-09 2021-09 /pmc/articles/PMC8351068/ /pubmed/33034229 http://dx.doi.org/10.1177/2192568220962439 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review Articles
Solaru, Samantha
Alluri, Ram K.
Wang, Jeffrey C.
Hah, Raymond J.
Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title_full Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title_fullStr Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title_full_unstemmed Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title_short Venous Thromboembolism Prophylaxis in Elective Spine Surgery
title_sort venous thromboembolism prophylaxis in elective spine surgery
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351068/
https://www.ncbi.nlm.nih.gov/pubmed/33034229
http://dx.doi.org/10.1177/2192568220962439
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