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Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia

BACKGROUND: The positive transcription elongation factor b (P-TEFb) kinase activity is involved in the process of transcription. Cyclin-dependent kinase 9 (CDK9), a core component of P-TEFb, regulates the process of transcription elongation, which is associated with differentiation and apoptosis in...

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Detalles Bibliográficos
Autores principales:	Qing, Yingjie, Wang, Xiangyuan, Wang, Hongzheng, Hu, Po, Li, Hui, Yu, Xiaoxuan, Zhu, Mengyuan, Wang, Zhanyu, Zhu, Yu, Xu, Jingyan, Guo, Qinglong, Hui, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351106/ https://www.ncbi.nlm.nih.gov/pubmed/34372855 http://dx.doi.org/10.1186/s12964-021-00764-5

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