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Divergent Regulation of Alveolar Type 2 Cell and Fibroblast Apoptosis by Plasminogen Activator Inhibitor 1 in Lung Fibrosis

Increased apoptosis sensitivity of alveolar type 2 (ATII) cells and increased apoptosis resistance of (myo)fibroblasts, the apoptosis paradox, contributes to the pathogenesis of idiopathic pulmonary fibrosis (IPF). The mechanism underlying the apoptosis paradox in IPF lungs, however, is unclear. Agi...

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Detalles Bibliográficos
Autores principales:	Jiang, Chunsun, Liu, Gang, Cai, Lu, Deshane, Jessy, Antony, Veena, Thannickal, Victor J., Liu, Rui-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Investigative Pathology 2021
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351125/ https://www.ncbi.nlm.nih.gov/pubmed/33887217 http://dx.doi.org/10.1016/j.ajpath.2021.04.003

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