Cargando…

Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State

The pathophysiology of coronavirus disease 2019 (COVID-19) involves multi-organ dysfunction, particularly involving the respiratory, cardiovascular and hematological systems. This dysfunction is partly due to systemic inflammation causing a wide array of pathological sequelae thus posing a significa...

Descripción completa

Detalles Bibliográficos
Autores principales: Ismail, Zeeshan, Salabei, Joshua K, Stanger, Greg, Asnake, Zekarias T, Frimer, Leora, Smock, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351253/
https://www.ncbi.nlm.nih.gov/pubmed/34381643
http://dx.doi.org/10.7759/cureus.16246
_version_ 1783735934523539456
author Ismail, Zeeshan
Salabei, Joshua K
Stanger, Greg
Asnake, Zekarias T
Frimer, Leora
Smock, Andrew
author_facet Ismail, Zeeshan
Salabei, Joshua K
Stanger, Greg
Asnake, Zekarias T
Frimer, Leora
Smock, Andrew
author_sort Ismail, Zeeshan
collection PubMed
description The pathophysiology of coronavirus disease 2019 (COVID-19) involves multi-organ dysfunction, particularly involving the respiratory, cardiovascular and hematological systems. This dysfunction is partly due to systemic inflammation causing a wide array of pathological sequelae thus posing a significant challenge to management despite the advances in treatment made thus far. In this report, we present a COVID-19 patient who developed a transient complete heart block and was temporarily paced as a complication of a saddle pulmonary embolus (PE). The mechanism of complete heart block is unclear, may be related to strain, ischemia, or vagal response. We believe that this is a unique sequence of events in a COVID-19 patient and, to our knowledge, is the first of its kind to be reported.
format Online
Article
Text
id pubmed-8351253
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-83512532021-08-10 Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State Ismail, Zeeshan Salabei, Joshua K Stanger, Greg Asnake, Zekarias T Frimer, Leora Smock, Andrew Cureus Cardiology The pathophysiology of coronavirus disease 2019 (COVID-19) involves multi-organ dysfunction, particularly involving the respiratory, cardiovascular and hematological systems. This dysfunction is partly due to systemic inflammation causing a wide array of pathological sequelae thus posing a significant challenge to management despite the advances in treatment made thus far. In this report, we present a COVID-19 patient who developed a transient complete heart block and was temporarily paced as a complication of a saddle pulmonary embolus (PE). The mechanism of complete heart block is unclear, may be related to strain, ischemia, or vagal response. We believe that this is a unique sequence of events in a COVID-19 patient and, to our knowledge, is the first of its kind to be reported. Cureus 2021-07-07 /pmc/articles/PMC8351253/ /pubmed/34381643 http://dx.doi.org/10.7759/cureus.16246 Text en Copyright © 2021, Ismail et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Ismail, Zeeshan
Salabei, Joshua K
Stanger, Greg
Asnake, Zekarias T
Frimer, Leora
Smock, Andrew
Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title_full Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title_fullStr Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title_full_unstemmed Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title_short Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
title_sort third-degree heart block associated with saddle pulmonary embolism: a rare sequelae of covid-19-induced hypercoagulable state
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351253/
https://www.ncbi.nlm.nih.gov/pubmed/34381643
http://dx.doi.org/10.7759/cureus.16246
work_keys_str_mv AT ismailzeeshan thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate
AT salabeijoshuak thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate
AT stangergreg thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate
AT asnakezekariast thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate
AT frimerleora thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate
AT smockandrew thirddegreeheartblockassociatedwithsaddlepulmonaryembolismararesequelaeofcovid19inducedhypercoagulablestate