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BSCI-07. Multiomics characterization of brain metastases in multiple histologies identifies enrichment of oxidative phosphorylation as a promising therapeutic target
PURPOSE: Brain metastasis (BM) is a lethal complication from systematic malignant tumors, and the incidence is approximately 10–30% of patients with advanced cancer. Extensive genomic analyses with large sample sets and the following functional studies revealed clinically relevant characteristics fo...
Autores principales: | Fukumura, Kazutaka, Malgulwar, Prit Benny, Fischer, Grant, Hu, Xiaoding, Zhang, Xiang, Yu, Dihua, Debeb, Bisrat, Davies, Michael, Huse, Jason |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351303/ http://dx.doi.org/10.1093/noajnl/vdab071.006 |
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