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Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report
We present a case of atypical recurrent optic neuritis. A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers. Lymph‐node biopsy was consistent with sarcoidosis. Aquaporin‐4 antibodies were also present. Three months following co...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351381/ https://www.ncbi.nlm.nih.gov/pubmed/34166585 http://dx.doi.org/10.1002/acn3.51413 |
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author | Foster, Michael A. Collorone, Sara Palace, Jacqueline Acheson, James Toosy, Ahmed T. |
author_facet | Foster, Michael A. Collorone, Sara Palace, Jacqueline Acheson, James Toosy, Ahmed T. |
author_sort | Foster, Michael A. |
collection | PubMed |
description | We present a case of atypical recurrent optic neuritis. A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers. Lymph‐node biopsy was consistent with sarcoidosis. Aquaporin‐4 antibodies were also present. Three months following corticosteroid treatment, his right optic neuritis relapsed, again with raised inflammatory markers. He was started on azathioprine and prednisolone with good effect. A dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin‐4 antibodies is very rare. Long‐term immunosuppression is required. The case highlights the importance of identifying the features and cause of atypical optic neuritis. |
format | Online Article Text |
id | pubmed-8351381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83513812021-08-15 Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report Foster, Michael A. Collorone, Sara Palace, Jacqueline Acheson, James Toosy, Ahmed T. Ann Clin Transl Neurol Case Study We present a case of atypical recurrent optic neuritis. A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers. Lymph‐node biopsy was consistent with sarcoidosis. Aquaporin‐4 antibodies were also present. Three months following corticosteroid treatment, his right optic neuritis relapsed, again with raised inflammatory markers. He was started on azathioprine and prednisolone with good effect. A dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin‐4 antibodies is very rare. Long‐term immunosuppression is required. The case highlights the importance of identifying the features and cause of atypical optic neuritis. John Wiley and Sons Inc. 2021-06-24 /pmc/articles/PMC8351381/ /pubmed/34166585 http://dx.doi.org/10.1002/acn3.51413 Text en © 2021 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Foster, Michael A. Collorone, Sara Palace, Jacqueline Acheson, James Toosy, Ahmed T. Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title | Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title_full | Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title_fullStr | Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title_full_unstemmed | Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title_short | Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
title_sort | sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351381/ https://www.ncbi.nlm.nih.gov/pubmed/34166585 http://dx.doi.org/10.1002/acn3.51413 |
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