Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound

Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one so...

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Detalles Bibliográficos
Autores principales: Farr, Ellen, Wolfe, Alexis R., Deshmukh, Swati, Rydberg, Leslie, Soriano, Rachna, Walter, James M., Boon, Andrea J., Wolfe, Lisa F., Franz, Colin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351384/
https://www.ncbi.nlm.nih.gov/pubmed/34247452
http://dx.doi.org/10.1002/acn3.51416
Descripción
Sumario:Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end‐expiration) for the post‐COVID‐19 compared to non‐COVID‐19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post‐COVID‐19.

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