Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound

Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one so...

Descripción completa

Detalles Bibliográficos
Autores principales: Farr, Ellen, Wolfe, Alexis R., Deshmukh, Swati, Rydberg, Leslie, Soriano, Rachna, Walter, James M., Boon, Andrea J., Wolfe, Lisa F., Franz, Colin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351384/
https://www.ncbi.nlm.nih.gov/pubmed/34247452
http://dx.doi.org/10.1002/acn3.51416
_version_ 1783735963212578816
author Farr, Ellen
Wolfe, Alexis R.
Deshmukh, Swati
Rydberg, Leslie
Soriano, Rachna
Walter, James M.
Boon, Andrea J.
Wolfe, Lisa F.
Franz, Colin K.
author_facet Farr, Ellen
Wolfe, Alexis R.
Deshmukh, Swati
Rydberg, Leslie
Soriano, Rachna
Walter, James M.
Boon, Andrea J.
Wolfe, Lisa F.
Franz, Colin K.
author_sort Farr, Ellen
collection PubMed
description Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end‐expiration) for the post‐COVID‐19 compared to non‐COVID‐19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post‐COVID‐19.
format Online
Article
Text
id pubmed-8351384
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-83513842021-08-15 Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound Farr, Ellen Wolfe, Alexis R. Deshmukh, Swati Rydberg, Leslie Soriano, Rachna Walter, James M. Boon, Andrea J. Wolfe, Lisa F. Franz, Colin K. Ann Clin Transl Neurol Brief Communications Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end‐expiration) for the post‐COVID‐19 compared to non‐COVID‐19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post‐COVID‐19. John Wiley and Sons Inc. 2021-07-11 /pmc/articles/PMC8351384/ /pubmed/34247452 http://dx.doi.org/10.1002/acn3.51416 Text en © 2021 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Communications
Farr, Ellen
Wolfe, Alexis R.
Deshmukh, Swati
Rydberg, Leslie
Soriano, Rachna
Walter, James M.
Boon, Andrea J.
Wolfe, Lisa F.
Franz, Colin K.
Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title_full Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title_fullStr Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title_full_unstemmed Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title_short Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
title_sort diaphragm dysfunction in severe covid‐19 as determined by neuromuscular ultrasound
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351384/
https://www.ncbi.nlm.nih.gov/pubmed/34247452
http://dx.doi.org/10.1002/acn3.51416
work_keys_str_mv AT farrellen diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT wolfealexisr diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT deshmukhswati diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT rydbergleslie diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT sorianorachna diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT walterjamesm diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT boonandreaj diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT wolfelisaf diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound
AT franzcolink diaphragmdysfunctioninseverecovid19asdeterminedbyneuromuscularultrasound

Ejemplares similares